Albert Barnes on Acts 8:32

The place, etc. Isa 53:7,8.

He was led, etc. This quotation is taken literally from the Septuagint. It varies very little from the Hebrew. It has been almost universally understood that this place refers to the Messiah; and Philip expressly applies it to him. The word "was led" ηχθη, implies that he was conducted by others; that he was led as a sheep is led to be killed. The general idea is that of meekness and submission when he was led to be put to death; a description that applies in a very striking manner to the Lord Jesus.

To the slaughter. To be killed. The characteristic here recorded is more remarkable in the sheep than in any other animal.

And like a lamb dumb, etc. Still, patient, unresisting.

So opened he not his mouth. He did not complain, or murmur; he offered no resistance, but yielded patiently to what was done by others.

(f) "He was lead" Isa 53:7,8