William Burkitt on Acts 16:6

Observe here, How the apostle and his companions had a desire and design to propagate the gospel in several provinces, but were forbidden by a secret impulse of the Holy Spirit.

Learn thence, That the frustrating our attempts, and disappointing our designs to preach the gospel to particular places, which we were purposed to go unto, doth sometimes arise from the Holy Ghost: the apostle intended to go into Bithynia, but the Spirit suffered him not. The very journeyings of the apostles, and first preachers of the gospel, as well as their divine exercises, were all ordered by the wisdom and will of God; they might neither speak, nor act, nor walk, but according to divine directions: They were forbidden by the Holy Ghost to preach the word in Asia. Thus Almighty God at pleasure orders the candle of the gospel to be removed out of one room into another, sends it from one place and people to another, and accordingly ought all places and persons to prize it highly, and improve it faithfully.