John Calvin on Jeremiah 49:17

Here again the Prophet confirms what he had said. We have before stated how necessary was such a repetition, because no one could have thought that destruction was so nigh the Idumeans. He did not then repeat what he had said, in order to explain more clearly what might have been otherwise obscure, but to fix more fully in the hearts of the faithful what appeared incredible.

He then says that Edom would become a waste; and then, that every one passing by it would be astonished and hiss on account of all her wounds, or strokes. Hissing may refer to derision, or to astonishment, or, at least, to wonder: for many hiss, or shake the head through mockery; and others hiss through wonder, when any unusual thing happens. And as he had said before, Whosoever shall pass through it shall be astonished, I am disposed to refer this also to what is produced by wonder or amazement. It afterwards follows —

Jeremiah 49:18

18. As in the overthrow of Sodom and Gomorrah and the neighbour cities thereof, saith the LORD, no man shall abide there, neither shall a son of man dwell in it.

18. Secundum subversionem Sodomae et Gomorrae et vicinarum ejus, dicit Jehova, non habitabit illie vir, et non manebit in ea filius hominis.