Adam Clarke on Ezekiel 26:21

Yet shalt thou never be found again - This is literally true; there is not the smallest vestige of the ancient Tyre, that which was erected on the main land. Even the ground seems to have been washed away; and the new Tyre is in nearly a similar state. I think this prophecy must be extended to the whole duration of Tyre. If it now be found to be in the state here described, it is sufficient to show the truth of the prophecy. And now it is found precisely in the state which the above prophetic declarations, taken according to the letter, point out! No word of God can ever fall to the ground.

Notwithstanding the former destructions, Tyre was a place of some consequence in the time of St. Paul. There was a Church there, (see Act 21:3, Act 21:4, etc.), which afterwards became famous. Calmet observes, it afforded a great number of martyrs for the Christian Church.