Adam Clarke on Genesis 28:14

Thy seed shall be as the dust - The people that shall descend from thee shall be extremely numerous, and in thee and thy seed - the Lord Jesus descending from thee, according to the flesh, shall all the families of the earth - not only all of thy race, but all the other families or tribes of mankind which have not proceeded from any branch of the Abrahamic family, be blessed; for Jesus Christ by the grace of God tasted death For Every Man, Heb 2:9.