Adam Clarke on Genesis 42:37

Slay my two sons, if I bring him not to thee - What a strange proposal made by a son to his father, concerning his grandchildren! But they show the honesty and affection of Reuben's heart; he felt deeply for his father's distress, and was determined to risk and hazard every thing in order to relieve and comfort him. There is scarcely a transaction in which Reuben is concerned that does not serve to set his character in an amiable point of view, except the single instance mentioned Gen 35:22 (note), and which for the sake of decency and piety we should wish to understand as the Targumists have explained it. See the notes.