Adam Clarke on Jeremiah 45:3

Thou didst say, Wo is me now! - All that were the enemies of Jeremiah became his enemies too; and he needed these promises of support.

The Lord hath added grief to my sorrow - He had mourned for the desolations that were coming on his country, and now he mourns for the dangers to which he feels his own life exposed; for we find, from Jer 36:26, that the king had given commandment to take both Baruch and Jeremiah, in order that they might be put to death at the instance of his nobles.