Adam Clarke on Lamentations 4:6

For the punishment - He thinks the punishment of Jerusalem far greater than that of Sodom. That was destroyed in a moment while all her inhabitants were in health and strength; Jerusalem fell by the most lingering calamities; her men partly destroyed by the sword, and partly by the famine.

Instead of no hands stayed on her, Blayney translates, "Nor were hands weakened in her." Perhaps the meaning is, "Sodom was destroyed in a moment without any human labor." It was a judgment from God himself: so the sacred text: "The Lord rained down fire and brimstone from the Lord out of heaven." See Gen 19:24.