Adam Clarke on Revelation 18:2

Babylon the great is fallen, is fallen - This is a quotation from Isa 21:9 : And he said, Babylon is fallen, is fallen; and all the graven images of her gods he hath broken unto the ground. This is applied by some to Rome pagan; by others to Rome papal; and by others to Jerusalem.

Is become - the hold of every foul spirit - See the parallel passages in the margin. The figures here point out the most complete destruction. A city utterly sacked and ruined, never to be rebuilt.