Jamieson, Fausset and Brown on 2 Timothy 4:5

5. I am no longer here to withstand these things; be thou a worthy successor of me, no longer depending on me for counsel, but thine own master, and swimming without the corks [Calvin]; follow my steps, inherit their result, and the honor of their end [Alford].

watch thou--literally, "with the wakefulness of one sober."

in all things--on all occasions and under all circumstances (Tit 2:7).

endure affliction--suffer hardships [Alford].

evangelist--a missionary bishop preacher, and teacher.

make full proof of--fulfil in all its requirements, leaving nothing undone (Ac 12:25; Ro 15:19; Col 4:17).