Jamieson, Fausset and Brown on Genesis 27:42-45

42-45. these words of Esau were told Rebekah--Poor woman! she now early begins to reap the bitter fruits of her fraudulent device; she is obliged to part with her son, for whom she planned it, never, probably, seeing him again; and he felt the retributive justice of heaven fall upon him heavily in his own future family.