Jamieson, Fausset and Brown on Hebrews 9:22

22. almost--to be joined with "all things," namely almost all things under the old dispensation. The exceptions to all things being purified by blood are, Ex 19:10; Le 15:5, &c.; 16:26, 28; 22:6; Nu 31:22-24.

without--Greek, "apart from."

shedding of blood--shed in the slaughter of the victim, and poured out at the altar subsequently. The pouring out of the blood on the altar is the main part of the sacrifice (Le 17:11), and it could not have place apart from the previous shedding of the blood in the slaying. Paul has, perhaps, in mind here, Lu 22:20, "This cup is the new testament in my blood, which is shed for you."

is--Greek, "takes place": comes to pass.

remission--of sins: a favorite expression of Luke, Paul's companion. Properly used of remitting a debt (Mt 6:12; 18:27, 32); our sins are debts. On the truth here, compare Le 5:11-13, an exception because of poverty, confirming the general rule.