Jamieson, Fausset and Brown on Isaiah 51:17

17. Awake, awake, stand up, O Jerusalem, &c.--(Is 52:1).

drunk--Jehovah's wrath is compared to an intoxicating draught because it confounds the sufferer under it, and makes him fall (Job 21:20; Psa 60:3; 75:8; Jr 25:15, 16; 49:12; Zec 12:2; Re 14:10); ("poured out without mixture"; rather, "the pure wine juice mixed with intoxicating drugs").

of trembling--which produced trembling or intoxication.

wrung ... out--drained the last drop out; the dregs were the sediments from various substances, as honey, dates, and drugs, put into the wine to increase the strength and sweetness.