Jamieson, Fausset and Brown on Isaiah 53:5

5. wounded--a bodily wound; not mere mental sorrow; literally, "pierced"; minutely appropriate to Messiah, whose hands, feet, and side were pierced (Psa 22:16). The Margin, wrongly, from a Hebrew root, translates, "tormented."

for ... for--(Ro 4:25; 2Co 5:21; He 9:28; 1Pe 2:24; 3:18)--the cause for which He suffered not His own, but our sins.

bruised--crushing inward and outward suffering (see on Is 53:10).

chastisement--literally, the correction inflicted by a parent on children for their good (He 12:5-8, 10, 11). Not punishment strictly; for this can have place only where there is guilt, which He had not; but He took on Himself the chastisement whereby the peace (reconciliation with our Father; Ro 5:1; Ep 2:14, 15, 17) of the children of God was to be effected (He 2:14).

upon him--as a burden; parallel to "hath borne" and "carried."

stripes--minutely prophetical of His being scourged (Mt 27:26; 1Pe 2:24).

healed--spiritually (Psa 41:4; Jr 8:22).