Jamieson, Fausset and Brown on Job 16:16

16. foul--rather, "is red," that is, flushed and heated [Umbreit and Noyes].

shadow of death--that is, darkening through many tears (La 5:17). Job here refers to Zophar's implied charge (Job 11:14). Nearly the same words occur as to Jesus Christ (Is 53:9). So Job 16:10 above answers to the description of Jesus Christ (Psa 22:13; Is 50:6, and Job 16:4 to Psa 22:7). He alone realized what Job aspired after, namely, outward righteousness of acts and inward purity of devotion. Jesus Christ as the representative man is typified in some degree in every servant of God in the Old Testament.