C. F. Keil and Franz Delitzsch on Deuteronomy 28:27

Deu 28:27-34

The second view depicts still further the visitation of God both by diseases of body and soul, and also by plunder and oppression on the part of their enemies. - In Deu 28:27 four incurable diseases of the body are threatened: the ulcer of Egypt (see at Exo 9:9), i.e., the form of leprosy peculiar to Egypt, elephantiasis (Aegypti peculiare malum: Plin. xxvi. c. 1, s. 5), which differed from lepra tuberosa, however, or tubercular leprosy (Deu 28:35; cf. Job 2:7), in degree only, and not in its essential characteristics (see Tobler, mediz. Topogr. v. Jerus. p. 51). עפלים, from עפל, a swelling, rising, signifies a tumour, and according to the Rabbins a disease of the anus: in men, tumor in posticis partibus; in women, durius quoddam οἴδημα in utero. It was with this disease that the Philistines were smitten (1Sa 5:1-12). גּרב (see Lev 21:20) and חרס, from חרס, to scrape or scratch, also a kind of itch, of which there are several forms in Syria and Egypt.