C. F. Keil and Franz Delitzsch on Proverbs 21:30

Pro 21:30 30 No wisdom and no understanding,      And no counsel is there against Jahve.

The expression might also be 'לפני ה; but the predominating sense would then be, that no wisdom appears to God as such, that He values none as such. With לנגד the proverb is more objective: there is no wisdom which, compared with His, can be regarded as such (cf. 1Co 3:19), none which can boast itself against Him, or can at all avail against Him (לנגד, as Dan 10:12; Neh. 3:37); whence it follows (as Job 28:28) that the wisdom of man consists in the fear of God the Alone-wise, or, which is the same thing, the All-wise. Immanuel interprets חכמה of theology, תּבוּנה of worldly science, עצה of politics; but חכמה is used of the knowledge of truth, i.e., of that which truly is and continues; תבונה of criticism, and עצה of system and method; vid., at Pro 1:2; Pro 8:14, from which latter passage the lxx has substituted here גבורה instead of תבונה. Instead of 'לנגד ה it translates πρὸς τὸν ἀσεβῆ, i.e., for that which is 'נגד ה against Jahve.