Matthew Poole and continuators on 2 Corinthians 6:3

3 Giving no offence in any thing , that the ministry be not blamed .

To give no offence signifies to avoid all actions which may be occasion of spiritual stumbling unto others, i. e. to make them to sin against God, or estrange their hearts from Christ, and the owning and profession of his Gospel. These words may be understood as a general Precept given to all Christians; So it agreeth with 1 Cor. 10.30, 32. or (which the following Verses seem most to favour) as referring to himself and Timothy, and other Ministers of the Gospel; like true Pastors of the Church of Christ, going out before the Flock, and shewing in their Example what they ought to be.

The Ministry here may either signifie the Office of the Ministry, or the Subject of it, the Gospel, which, ch. 5.18. is called the Ministry of Reconciliation; not only the Office of the Ministry, but the Gospel it self, suffereth by the scandalous conversation of Ministers and private Christians; ignorant persons being not able, or not willing, to distinguish betwixt the faults of persons, and the faults of a Doctrine or Office.