Matthew Poole and continuators on Ephesians 6:18

18. Praying always , with all prayer and supplication in the Spirit , and watching thereunto with all perseverance , and supplication for all saints .

i. e. In every opportunity, so often as our own, or others necessities call us to it, 1 Thess. 5.17.

Prayer when opposed to supplication seems to signifie petitioning for good things, and supplication the deprecating of evil, 1 Tim. 2.1.

Either our own Spirit with which we pray, so as not to draw nigh to God with our Mouth onely, as Isa. 29.13. Or rather the Holy Spirit of God by whose assistance we pray, Rom. 8.26, 27. Iude 20.

To Prayer, in opposition to sloth and security. See Mat. 26.41. Col. 4.2. and 1 Pet. 4.7.

Constancy and continuance in Prayer in every condition adverse as well as prosperous, though Prayer be not presently answered, Luk. 18.1.

Not onely for our selves, but for our Brethren in the world, none being in so good a condition but they may need our Prayers.

Marginal references: Mark. 13.33.