Matthew Poole and continuators on Galatians 4:29

29 But as then he that was born after the flesh , persecuted him that was born after the spirit , even so it is now .

As it was in Abrahams time, Ishmael, who was born in a meer carnal and ordinary way of Generation:

Persecuted Isaac, by mocking at him, Gen. 21.9. who was born by vertue of the promise, and the mighty power of God, inabling Sarah at those years to conceive, and Abraham to beget a Child.

Even so it is now, the carnal Seed of Abraham, the Jews persecute the Christians which are his Spiritual Seed. From whence we may observe, that the Holy Ghost accounteth mockings of good people for Religion, Persecution. So Heb. 11.36. others had tryals of cruel mockings, and we know these were one kind of the sufferings of Christ. By this also the Apostle doth both confirm, what he had before said, in making Hagar a Type of the Jews, and Sarah a Type of the Gentiles, the Jews persecuting the seed of Christ, as Hagars seed persecuted Isaac.