Matthew Poole and continuators on Genesis 22:17

17 That in blessing, I will bless thee, and in multiplying I will multiply thy seed, as the stars of the heaven, and as the sand which is upon the sea shore, and thy seed shall possess the gate of his enemies:

(i. e.) The City, by an usual Synecdoche, as Deut. 12. 15. and 18. 6. all the Cities and consequently the Country adjacent: gate for gates. The sense is, they shall subdue their Enemies. For the gates of Cities were the places both of jurisdiction or judicature, Deut. 21. 19. and 22. 15. Amos 5. 12, 15. Zech. 8. 16. and of fortification and chief strength in War, Iudg. 5. 8. Psal. 147. 13. Isa. 22. 7. Ezek. 21. 22. And this promise was fulfilled both literally in Israels conquest of Canaan, in David, Solomon, &c. and spiritually in Christ, Psal. 110. 1, 2, 3.

Marginal references: Heb. lip.