Matthew Poole and continuators on Genesis 31:21

21 So he fled with all that he had, and he rose up and passed over the river , and set his face toward the mount Gilead .

Euphrates, which lay between Mesopotamia and Chaldea, Gen. 15. 18. which for its largeness and famousness is oft called the River emphatically, as Exod. 23. 31. Ios. 24. 2, 3. &c.

(i. e.) Resolutely directed his course. See Ier. 50. 5. Luk. 9. 51, 53.

A very high and long mountain beyond Iordan adjoyning to the Mountain of Lebanon, at the foot of which there was a large and fruitful country which from the Mountain received the name of Gilead, Deut. 34. 1. Ier. 8. 22. and 22. 6. This Mountain is here called Gilead by anticipation, as appears from ver. 48.