Matthew Poole and continuators on Hebrews 12:3

3 For consider him that endured such contradiction of Sinners against himself, lest ye be wearied and faint in your minds.

The connection is rational, that they ought to regard this example, for that there were greater Sufferings behind than any yet they had endured, which would inforce it, as v. 4. [non-Latin text not transcribed], signifieth the use of a proportionable consideration, thinking on, or reasoning about this Example within a Man's self, such as may make the Considerer bear a proportion to the Subject considered,

this Jesus spoken of before, who most patiently submitted to, and perseveringly bore up under such opposition and contradiction by the Words and Works of the most wicked and vilest Men against himself, who was the most innocent and best of Men, always going about doing good to them, so as their Sin and his Patience were without Parallel; none was ever so Scorned, Taunted, Reviled, Blasphemed, Spit on, and Ignominiously treated like him; and never any so invincibly endured it, Rom. 15.3.

The reason of this consideration is, lest faintness, languishing, or deficiency of Soul, that is, of vigour, strength and activity of heart in Grace should befall them, and so they should lye down and cease to run the Christian Race, which the Devil designed to oblige them to, as he would Christ, by the multitude and soreness of the contradictions, they should suffer from Sinners in it, so greatly as would not end but by broaching their Life Blood, as they did Christs, and these must expect from them.