Matthew Poole and continuators on Isaiah 1:4

4 Ah sinful Nation, a People laden with iniquity , a seed of evil-doers , children that are corrupters , they have forsaken the LORD , they have provoked the holy One of Israel unto anger , they are gone away backward .

This Particle implies both his wonder, and anger, and grief, and shame that they were such.

Heb. Of heaviness of iniquity, i. e. of heavy or great sins, for heavy is commonly put for great or grievous, as Isa. 21. 15. and 30. 27. Laden not with the sense of sin, as Mat. 11. 28. but with the guilt and bondage of sin.

The Children of wicked Parents, whose guilt they inherit, and whose evil Example they follow.

Heb. that corrupt, to wit, themselves or their ways, or others by their counsel and example. Or, that destroy themselves and their land by their wickedness.

Not in profession, but in practice and reality, neglecting or corrupting his Worship, refusing his yoke and conduct.

They have lived as if it were their great design and business to provoke him.

Instead of proceeding forward and growing in grace, which was their duty, they are all faln from their former professions, and grown worse and worse, and have impudently turned their backs upon me.

Marginal references: Heb. of heaviness.; Heb. alienated; Or, separated. Psal. 58. 3.