Matthew Poole and continuators on Isaiah 6:10

10 Make the heart of this people fat , and make their ears heavy , and shut their eyes : lest they see with their eyes, and hear with their ears, and understand with their heart, and convert and be healed .

i. e. Stupid and senseless: For the Fat which is in the Body is without sense; and Fatness in the Heart, makes it dull and heavy. Thus this Phrase is used, Psal. 119. 70. And this seems best to agree with the following Words. This making of their Hearts fat is here ascribed to the Prophet, as it is ascribed to God in the repetition of this Prophecy, Ioh. 12. 40. because God inflicted this Judgment upon them by the Ministry of the Prophet, partly by way of Prediction, foretelling that this would be the effect of his Preaching; and partly by way of Judicial Operation, withdrawing the Light and Help of his Spirit, and giving them up to the Power and Arts of Satan, and to their own Mistakes and Lusts, whereby they are easily and commonly led to turn God's Word, as they do other things, into Occasions of Sin.

Make them dull of hearing, as Isa. 59 1. Zech. 7. 11. as sometimes the Ears are made by an excessive Noise.

Heb. dawb their eyes, as the Word is used also Isa. 44. 18.

That they may not be able, as before they were not willing, to see.

Turn from their sinful Practices, unto God.

Of Sin, which is the Disease of the Soul, by Remission and Sanctification, and of all the deadly Effects of Sin.

Marginal references: Jer. 5. 21.