Matthew Poole and continuators on Jeremiah 4:25

25 I beheld, and lo, there was no man , and all the birds of the heavens were fled .

Quite depopulated and laid waste, all either slain, or carried captive, or fled: for after the flight of Men, Women and Children into Egypt, upon the death of Gedaliah, scarce a Jew left in Iudea.

Such birds as are used to inhabit places, that live, feed and build among men, others indeed, both birds and beasts would continue, which implies but the greater desolation, and wast of the Land, as is threatned against Babylon; Isa. 13.19, 20, 21, 22. either to seek provisions, here being no food left for them, or frighted with the hideous noises and clatterings that do attend Armies; as we have read, that such hath been the concussion of the Air by the loud clamours and noises of Armies, that birds have fallen down to the earth, chap. 9.10. Zeph. 1.2, 3.