Matthew Poole and continuators on Jeremiah 7:32

32 Therefore behold, the dayes come, saith the LORD, that it shall no more be called Tophet, nor the valley of the Son of Hinnom, but the valley of slaughter: for they shall bury in Tophet till there be no place.

They were called so after this, and are known by those names to this day, but the meaning is, they shall acquire a name from another occasion, that shall suit them as well, viz. for the great slaughter that shall be made there, or rather thereabouts in, and about Jerusalem, and therefore called the valley of slaughter, from the effect of slaughter; as Judas his field was called Akeldama, Acts 1.19. being a place for burying of the slain, as the next words shew.

Either there shall be so great a slaughter made upon that spot by the Chaldeans, that they shall bury as many, as the place will contain, and the rest of the Carcases they shall throw on heaps, to rot above-ground; for to lye unburied, is frequently used as a curse on such, the burying of the dead being accounted as a thing sacred, and a significant symbol of the Res[illegible: 1 letter]rrection, or those that are slain in, and about Ierusalem at the Siege, and taking of it, shall be carried thither to be buried, either because there shall be no burying places left about Jerusalem, or that valley shall be filled, till there be no place for more, that hereby it may be so polluted, that no thoughts of holiness may remain in it: for a dead Carcase under the Law was unclean; and that which before was a valley of pleasure, and great delight, and they had dedicated to God, shall now be a vall[illegible: 1 letter]y of slaughter.

Marginal references: chap. 16.6.