Charles H. Spurgeon on Psalms 104:15

Wine that maketh glad the heart of man. The wine mentioned had the quality of fermented liquors; it gladdened the heart. Thus, if taken to excess, it would have led to intoxication. The Hebrew term is "yayin", answering to the Greek oinos, and including every form which the juice of the grape might be made to assume as a beverage. It was this of which Noah partook when he became drunken (Ge 9:21,24). Melchizedek brought it forth to Abraham (Ge 14:18). Lot's daughters gave it to their father and made him drunk (Ge 14:35). From this the Nazarite was to separate himself (Nu 6:3-20). This is the highly intoxicating drink so often mentioned by Isaiah (Isa 5:11-22 12:13 28:1-7); but just because of this, it might become to man one of those mercies in connection with the use of which he was to exercise constant self control. Taken to excess it was a curse; enjoyed as from God, it was something for which man was called to be thankful. John Duns.