Charles H. Spurgeon on Psalms 139:21

And am not I grieved with those that rise up against thee? The expression here —"grieved" —explains the meaning of the word "hate" in the former member of the verse. It is not that hatred which is followed by malignity or ill will; it is that which is accompanied with grief, pain of heart, pity, sorrow. So the Saviour looked on men: Mr 3:5: —"And when he had looked round about on them with anger, being grieved for the hardness of their hearts." The Hebrew word used here, however, contains also the idea of being disgusted with; of loathing; of nauseating. The feeling referred to is anger —conscious disgust —at such conduct; grief, pain, sorrow, that men should evince such feelings towards their Maker. —Albert Barnes.