Charles H. Spurgeon on Psalms 141:8

But mine eyes are unto thee, O GOD the Lord. He looked upward and kept his eyes fixed there. He regarded duty more than circumstances; he considered the promise rather than the external providence; and he expected from God rather than from men. He did not shut his eyes in indifference or despair, neither did he turn them to the creature in vain confidence, but he gave his eyes to his God, and saw nothing to fear. Jehovah his Lord is also his hope. Thomas called Jesus Lord and God, and David here speaks of his God and Lord. Saints delight to dwell upon the divine names when they are adoring or appealing. In thee is my trust. Not alone in thine attributes or in thy promises, but in thyself. Others might confide where they chose, but David kept to his God: in him he trusted always, only, confidently, and unreservedly. Leave not my soul destitute; as it would be if the Lord did not remember and fulfil his promise. To be destitute in circumstances is bad, but to be destitute in soul is far worse; to be left of friends is a calamity, but to be left of God would be destruction. Destitute of God is destitution with a vengeance. The comfort is that God hath said, "I will never leave thee nor forsake thee."