John Trapp on Revelation 16:10

Verſe 10. Ʋpon the ſcat of the Beast] This City of Rome, which was never yet beſieged (ſince it became the ſeat of Antichriſt) but it was taken, and ſhall be again ſhortly to purpoſe.

And his kingdome was full of darkneſſe] It appeared to be ſo (as motes appear in the Sun-ſhine) by the clear light of truth ſhining upon it. A Scotiſh mist is here already fallen upon a piece of his Kingdome: and what further ſervice God hath for their and our armies to do againſt the Pope in Ireland, or elſwhere, [non-Latin text not transcribed]. we expect and pray. God grant us good agreement among our ſelves, and then much may be done abroad.

And they gnawed their tongues] Being as mad with malice, as Boniface the 8. was of diſcontent; who being ſuddenly taken priſoner at his fathers houſe by Sarah Columnus his mortall enemy,Turk. hiſt. 126. and brought to Rome, laid up in the Caſtle of S. Angelo, within 35. daies after, moſt miſerably died in his madnes, renting himſelf with his teeth, and devouring his own fingers.