John Wesley on Ecclesiastes 1:15

Crooked - All our knowledge serves only to discover our miseries, but is utterly insufficient to remove them; it cannot rectify those disorders which are either in our own hearts and lives, or in the men and things of the world. Wanting - In our knowledge. Or, counted out to us from the treasures of human learning. But what is wanting, will still be so. And that which is wanting in our own knowledge, is so much that it cannot be numbered. The more we know, the more we see of our own ignorance.