John Wesley on Isaiah 13:3

Sanctified ones - The Medes and Persians, so called, because they were set apart by God, for this holy work of executing his just vengeance. Mighty ones - Those whom I have made mighty for this work. Highness - Or, as others render it, in my glory, in the doing of that work which tends to the advancement of my glory. Tho' the Medes had no regard to God, but only to their own ends.