John Wesley on Isaiah 59:12

Transgressions - The word here signifies sins of an high nature, such as wherein there is much of man's will against light: rebellious sins. Multiplied - They admit of no excuse; for they are acted before thee, and multiplied against thee, whereby thou art justly provoked to deny us all help. Testify - As so many witnesses produced proves our guilt. Are with us - Are still unforgiven. We know - We are convinced of them.