John Wesley on Leviticus 17:11

Is in the blood - Depends upon the blood, is preserved and nourished by it. The blood maketh atonement - Typically, and in respect of the blood of Christ which it represented, by which the atonement is really made. So the reason is double; because this was eating up the ransom of their own lives, which in construction was the destroying of themselves. because it was ingratitude and irreverence towards that sacred blood of Christ which they ought to have in continual veneration.