John Wesley on Psalms 22:26

Satisfied - This is doubtless to be understood, of those spiritual blessings, that grace and peace, and comfort, which all believing souls have in the sense of God's love, the pardon of their sins, and the influences of God's spirit. Seek him - That seek his favour. Your heart - He speaks of the same persons still, though there be a change from the third to the second person, as is usual in these poetical books. For ever - Your comfort shall not be short and transitory, as worldly comforts are, but everlasting.