John Wesley on Romans 1:23

And changed - With the utmost folly. Here are three degrees of ungodliness and of punishment: the first is described, Rom 1:21 - 24; the second, Rom 1:25 - 27; the third, in Rom 1:28, and following verses. The punishment in each case is expressed by God gave them up. If a man will not worship God as God, he is so left to himself that he throws away his very manhood. Reptiles - Or creeping things; as beetles, and various kinds of serpents.